The Success Of GLP-1s Could Cause A Boom In Medical Aesthetics Next

Mentioned:

GLP-1s have quickly become one the single most successful pharmaceutical products ever. And now, they might be causing a new boom in medical aesthetics.

What’s happening:

Multiple private and public companies have been investing in clinical research and new product development targeting the aesthetic effects caused by GLP-1 induced rapid weight loss

By the numbers:

Boston Consulting Group estimates that provider revenue from treating post-GLP-1 aesthetic concerns will grow from roughly $700M USD to $2B USD within the next four years

Why it matters:

McKinsey publicly stated in a research report that 63% of patients seeking facial aesthetics after GLP-1 weight loss were not previously active users of medical aesthetic treatments

Who is making moves:

Conexeu Sciences (NASDAQ: CNXU) has publicly stated they are aiming to position their proprietary CXU platform for medical aesthetics and facial and body tissue restoration
South Korea’s L&C Bio is developing an injectable product known as MegaAdipoECM which is aiming to provide a biological scaffold into which the patient’s own cells can migrate into and repopulate the area to deal with facial volume loss and skin laxity from GLP-1 weight loss
Rapalogix Health raised a $20M USD Series A financing round to advance their skincare line and complete Investigation New Drug work for their aesthetic dermatology drug RLX-202
Pharmaceutical giant Galderma has made GLP-1 facial volume loss a meaningful research priority over the last year and a half and Chief Executive Officer Flemming Ornskov publicly stated that GLP-1 patients have started to provide an early boost to their aesthetics and injectables business

Going deeper:

GLP-1 weight loss can strip fat faster than skin can adapt and most current options add temporary volume as opposed to restoring and rebuilding the tissue itself
Conexeu Sciences’ CXU platform’s first regulatory step is in wound care, where the United States Food and Drug Administration has provided pre-submission feedback for their initial wound care indiction
Conexeu Sciences’ Chief Executive Officer Miles Harrison previously ran Galderma North America which is the business behind Resylane and Sculptra, two of the biggest existing products in the aesthetics market
The 12 month preclinical trial completed completed by Conexeu Sciences demonstrated that their CXU platform met its objective for tissue restoration in a facial model and is designed to be delivered through a fine-gauge needle for precise placement to support the tissue changes that can follow GLP-1 weight loss, including both facial volume loss as well as skin laxity

The intrigue:

Conexeu Sciences is currently the only private or public company whose stated target includes body tissue restoration and is not strictly limited to facial tissue

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